Country for PR: Hong Kong
Contributor: PR Newswire Asia (Hong Kong)
Monday, March 25 2019 - 17:31
AsiaNet
Kazia to present on Cantrixil at American Association for Cancer Research (AACR) 2019 Annual Meeting
SYDNEY, March 25, 2019 /PRNewswire-AsiaNet/ --

Australian oncology-focused biotech company Kazia Therapeutics Ltd (ASX: KZA, 
NASDAQ: KZIA) has been selected to present data from the Phase I study of 
Cantrixil in ovarian cancer at the American Association for Cancer Research 
(AACR) 2019 Annual Meeting.

Logo - https://photos.prnasia.com/prnh/20171120/1996749-1LOGO 

AACR's Annual Meeting is one of the top-tier academic conferences worldwide and 
brings together around 20,000 representatives from academia, industry, 
government and advocacy organisations from across the globe. The meeting is 
being held from 29 March to 3 April at the Georgia World Congress Center in 
Atlanta, Georgia, USA.

Clinical Program Director, Daniel Berg will be presenting on Kazia's Cantrixil 
Phase I in ovarian cancer at the event on 1 April 2019. Mr Berg will present 
data from Part A of the study -- the dose escalation component -- which 
completed recruitment in October 2018.

TRX-E-002-1 (Cantrixil), is a third-generation benzopyran molecule with 
activity against cancer stem cells and is being developed to treat ovarian 
cancer. It was developed in Australia and initial preclinical studies were 
conducted at Yale University. Cantrixil was granted orphan designation for 
ovarian cancer by the US FDA in April 2015.

The abstract presentation is entitled: Phase I Study of Intraperitoneal 
TRX-E-002-1 in Patients with Persistent or Recurrent Ovarian Cancer, Fallopian 
Tube Cancer or Primary Peritoneal Cancer: Results of Dose-Escalation Phase.

The abstract has been authored by the trial's Principal Investigators (PIs) - 
led by the two primary PIs in Australia and the US: Associate Professor 
Jermaine Coward at the ICON Cancer Care in Brisbane, Queensland and Dr Don 
Dizon at the Lifespan Cancer Institute at Rhode Island Hospital. The trial is 
being conducted across six sites in the US and Australia as follows:

Country	     State	     Site	                  Principal Investigator

US	     Rhode Island    Lifespan Cancer Institute,   Dr. Don Dizon
                             Providence

US	     Oklahoma	     Stephenson Cancer Center,    Assoc. Prof. Kathleen Moore
                             Oklahoma City

US	     Texas	     Mary Crowley Cancer          Dr. Minal Barve
                             Research Centre, Dallas

Australia    Queensland	     ICON Cancer Care, Brisbane   Assoc. Prof. Jermaine 
                                                          Coward

Australia    New South Wales Westmead Hospital, Sydney    Prof. Paul Harnett

Australia    South Australia Flinders Medical Centre,     Dr. Ganessan 
                             Adelaide	                  Kichenadasse

"The key objective with Part A of the Phase I study was to assess the safety of 
the drug and find the right dose level to take the study to the next stage. We 
are delighted to be presenting our data at the AACR meeting and we look forward 
to discussing our findings with clinicians and potential partners," said 
Cantrixil Program Director Daniel Berg.

The presentation session details are as follows:

Session Title: Phase I Clinical Trials: Part 3
Date and Time: Monday April 1, 2019 1:00 PM - 5:00 PM
Location: Georgia World Congress Center, Exhibit Hall B, Poster Section 16
Poster Board Number: 15
Permanent Abstract Number: CT091

Interested parties are encouraged to attend and can add the session to their 
itinerary here: https://www.abstractsonline.com/pp8/#!/6812/session/1315

Meanwhile, the link to the abstract is here: 
https://www.abstractsonline.com/pp8/#!/6812/presentation/9899

The content of the abstract and presentation is embargoed until the start of 
the conference when it will be available through the above link and on the 
Kazia website.

***ENDS***

For more information on Kazia Therapeutics or Cantrixil, please visit: 
www.kaziatherapeutics.com

SOURCE  Kazia Therapeutics Ltd