The CDMO segment of the world's leading biotech company GenScript announced 
that GenScript's plasmid and virus facility was put into operation on December 
18, 2019. It is a milestone on the path to industrialization of the gene and 
cell therapy industry, pioneered by GenScript. GenScript's plasmid and virus 
facility is going to be China's largest plasmid and virus facility that meets 
the needs in clinical stage.

The virus facility that put into use in Zhenjiang has been built in strict 
compliance with GMP and is completely used for the manufacturing of viral 
vectors in gene and cell therapy products. The facility has capability to 
manufacture viral vectors for clinical phase I/II. As the facility was designed 
and constructed by the team from an international professional pharmaceutical 
company, the facility features first-class design and capacity in the industry.

At this event, Dr. Brian Min, CEO of GenScript BDBU delivered a speech. Dr. 
Brian said, "Cancer treatments have been evolving nowadays. With the rapid 
development of life sciences and medicine, gene and cell therapy (GCT) 
technology has been one of the areas most concerned in recent years. GenScript 
has made remarkable achievements in GCT. In response to expedited 
industrialization of the GCT market, with 17 years of CRO experience, GenScript 
has engaged BDBU in biologics CDMO and developed and innovated in our GCT 
vector platform, helping GCT customers address vector production challenges 
during product development. Supported by powerful manufacturing teams, advanced 
technology, and rich experience, GenScript has consistently offered customized 
services to customers and practiced the individualized management model. 
GenScript is able to help customers effectively diversify risks, lower costs 
and shorten the production cycle, promoting the industrialization of GCT 
products. With experience in more than 10 IND programs and more than 50 batches 
of pilot scale production, GenScript will continue to provide customers with 
optimum services. GenScript is expected to contribute to the development of the 
GCT industry."

The guests visited GenScript plasmid and virus facility. The total facility 
area is about 5,000m2, and is currently the largest plasmid and virus facility 
in China. Both plasmid facility and virus facility are equipped with 4 parallel 
production lines, which allows more than 20 process development projects to be 
conducted in the whole year. The team leaders from GenScript Gene and Cell 
Therapy Vector Platform have more than 10 years of experience in vector 
manufacturing, and the platform is currently working on over 10 IND projects. 
The overall design, layout and quality management system of the facility are 
established in strict compliance with GMP. The GMP virus facility put into 
production this time can provide customers with clinical viral vectors 
manufacturing services and help to accelerate the conversion of the projects 
from preclinical research to clinic.

GenScript will also provide commercial manufacturing of plasmid and virus in 
the near future. The ground-breaking of the commercial manufacturing was held 
in April 2019 and will be officially put into production in the first quarter 
of 2021. By then, GenScript will become the first CDMO in China to have a 
commercial manufacturing center for gene and cell therapy vectors, providing 
customers with a one-stop solution from clinical to commercial services, 
thereby accelerating the IND application of gene cell therapy products and 
promoting development of industrialization of gene and cell therapy.

About GenScript

GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology 
group. GenScript's businesses encompass four major categories based on its 
leading gene synthesis technology, including operation as a Life Science CRO, 
enzyme and synthetic biology products, biologics development and manufacturing, 
as well as cell therapy.

Founded in 2002 and listed on the Hong Kong Stock Exchange in 2015, GenScript 
has an established global presence across Greater China, North America, the EU, 
and Asia Pacific. Today, over 300,000 customers from over 160 countries and 
regions around the world have used GenScript's premier, convenient, and 
reliable products and services.

GenScript currently has more than 3,000 employees globally, 33% of whom hold 
master's and/or Ph.D. degrees. In addition, GenScript has a number of leading 
commercial technologies developed in the fields of synthetic biology, 
immunotherapy, antibody design, chemical synthesis and bioinformatics, 
including more than 70 patents and over 200 patent applications. As of January 
2019, GenScript's products and services have been cited by 36,500 scientific 
papers worldwide.

GenScript is committed to striving towards its vision of being the most 
reliable biotech company in the world to make humans and nature healthier 
through biotechnology.

source: GenScript Biotech Corporation