Country for PR: United Kingdom
Contributor: PR Newswire Europe
Saturday, February 01 2020 - 03:23
AsiaNet
Oxford Nanopore Sequencers Have Left UK for China, to Support Rapid, Near-sample Coronavirus Sequencing for Outbreak Surveillance
OXFORD, England, Feb. 1, 2020 /PRNewswire-AsiaNet/--

Following extensive support of, and collaboration with, public health 
professionals in China, Oxford Nanopore has shipped an additional 200 MinION 
sequencers and related consumables to China. These will be used to support the 
ongoing surveillance of the current coronavirus outbreak, adding to a large 
number of the devices already installed in the country.

Oxford Nanopore is already working to support more than 100 public health 
laboratories in China, as well as a number of Chinese microbiology laboratories 
and global public health scientists, with a growing community of scientists 
taking part in the surveillance process.

"We are privileged to be working with a global scientific community to support 
their understanding of this outbreak," said Dr Gordon Sanghera, CEO, Oxford 
Nanopore. "We hope that the nanopore vision of enabling anyone to access 
biological information, anywhere, can have a positive impact, and are immensely 
grateful for the community support as we work to rapidly optimise for this 
outbreak."

The MinION sequencer was designed for broad accessibility. It weighs under 100g 
and is run with a laptop or special accessory, the MinIT, to perform data 
analysis. It streams sequence data in real time, allowing for rapid sequencing. 
It is well suited to rapid sequencing in distributed locations. Previously, the 
device has performed sequencing in rural or remote settings, for example in 
understanding Ebola, Zika or TB.

"We were able to generate results less than 24 hours after receiving an 
Ebola-positive sample, with the sequencing process taking as little as 15 to 60 
minutes. We show that real-time genomic surveillance is possible in 
resource-limited settings and can be established rapidly to monitor outbreaks." 
– Josh Quick, University of Birmingham, Nature, 2016 
https://www.nature.com/articles/nature16996

Rapid sequencing of the coronavirus has been one essential tool in 
understanding the outbreak. Sequence information is typically combined with 
location and time data to provide an insight into how the virus is spreading 
and whether it is changing.

Oxford Nanopore's sequencing technology has been used in many of the early 
coronavirus genomes from China, including the first genome published in NEJM 
and the "cluster" of genomes that indicated human-to-human transmission that 
were published in the Lancet and the first genomes published from the US.

Researchers in the scientific community have developed protocols for nanopore 
sequencing of nCoV; Oxford Nanopore is working with the scientific community in 
the optimisation of those protocols.

If you are interested in following updates on the use of nanopore in this 
outbreak, please follow this post 
[https://nanoporetech.com/about-us/news/novel-coronavirus-ncov-2019], and if 
you would like to get in touch for nCoV specific support, please use this form 
[https://register.nanoporetech.com/ryi-novel-coronavirus].

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Source: Oxford Nanopore Technologies
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