Country for PR: United States
Contributor: PR Newswire New York
Tuesday, September 29 2020 - 22:00
AsiaNet
Cardiac Dimensions Announces $17.5 Million Series C Financing to Accelerate Sales Expansion of The Carillon Mitral Contour System(R)
KIRKLAND, Washington, Sept. 29, 2020 /PRNewswire-AsiaNet/ --

  -- Funds to be Used for Commercial Expansion in Europe and Australia

Cardiac Dimensions(R), a leader in the development of innovative, minimally 
invasive treatments for functional mitral regurgitation (FMR) in patients with 
heart failure, today announced the company has closed a $17.5 million Series C 
financing. All existing shareholders participated in the round including 
Aperture Venture Partners, Arboretum Ventures, Hostplus, Life Sciences 
Partners, Lumira Ventures, and M. H. Carnegie & Co.

The financing will be used to accelerate commercial sales of Cardiac 
Dimensions' Carillon Mitral Contour System(R) in Europe and allow for expansion 
into other geographies such as Australia. Earlier this month, Australia's 
Therapeutic Goods Administration approved the Carillon System for commercial 
use in FMR patients with mild to severe mitral regurgitation.

"The Carillon System is a transformative product which has shown great success 
in helping an extremely large patient population with very few options," said 
Rick Wypych, Chief Executive Officer and President of Cardiac Dimensions. "The 
new round of financing will allow for continued growth of sales in Europe and 
provide capital for our expansion efforts into other geographies–such as 
Australia. We thank our investors for their continued support as our business 
shows excellent results despite the challenging environment."

An estimated 26 million people, worldwide, suffer from heart failure(i) and of 
those, approximately 70 percent have functional mitral regurgitation. FMR is 
due to the mitral valve not closing tightly, resulting in blood flowing or 
leaking backwards through the mitral valve. This further decreases the amount 
of oxygenated blood that is pumped out to the body, increases the symptoms 
associated with heart failure, and decreases the quality of life of those who 
have been diagnosed. 

"We're excited to support the expansion of sales of the Carillon System," said 
Trevor Moody of M. H. Carnegie & Co. "Cardiac Dimensions' innovative efforts 
and dedication to expanding access to the Carillon System will soon allow 
people worldwide to benefit from this therapeutic innovation."

About the Carillon Mitral Contour System

The Carillon System offers a simple right heart approach to transcatheter 
mitral valve repair designed to reshape the anatomy and function of the mitral 
apparatus from the coronary sinus. Distal and proximal anchors, connected by a 
shaping ribbon, utilize the heart's venous anatomy to cinch the mitral 
apparatus without compromising the valve or future treatment options.(ii,iii) 
The Carillon System is designed to treat the primary cause of functional mitral 
regurgitation in patients with MR grades 2+, 3+ and 4+ and is the first and 
only device to demonstrate a reduction in regurgitant volume and favorable left 
ventricular remodeling in a randomized sham-controlled clinical trial of 
percutaneous valve therapy.(iv,v,vi ) The Carillon System is CE-marked (0344) 
and has been implanted in over 1,200 patients in the U.S., Europe, Australia, 
Turkey and the Middle East. The Carillon System is currently being studied in 
The CARILLON Trial pivotal trial and limited to investigational use in the 
United States.

About Cardiac Dimensions

Cardiac Dimensions is a leader in the development of innovative, minimally 
invasive treatments to address heart failure and related cardiovascular 
conditions. Privately held, the company's lead investors include Aperture 
Venture Partners, Arboretum Ventures, HostPlus, Life Sciences Partners, Lumira 
Ventures and M.H. Carnegie & Co. Cardiac Dimensions is headquartered in 
Kirkland, Washington and has operations in the United States, Australia and 
Germany. For more information, visit www.cardiacdimensions.com.

(i) Lipiecki J, Kaye DM, Witte KK, et al. Long-Term Survival Following 
Transcatheter Mitral Valve Repair: Pooled Analysis of Prospective Trials with 
the Carillon Device. Cardiovascular Revascularization Medicine. Advance online 
publication. doi:10.1016/j.carrev.2020.02.012.
(ii) Hoppe UC, Brandt MC, Degen H, et al. Percutaneous mitral annuloplasty 
device leaves free access to cardiac veins for resynchronization therapy. 
Catheter Cardiovasc Interv. 2009;74(3):506-11.
(iii) Latib, A. "Coronary Sinus Annuloplasty." New York, Montefiore Medical 
Center.
(iv) Lipiecki J, Siminiak T, Sievert H, et al. Coronary sinus-based 
percutaneous annuloplasty as treatment for functional mitral regurgitation: the 
TITAN II trial. BMJ Open Heart. 2016; 3
(v) Siminiak T, et. al. Treatment of functional mitral regurgitation by 
percutaneous annuloplasty: Results of the TITAN Trial. Eur J Heart Fail. 
2012;14:931-38.
(vi) Sievert, H. 2018. REDUCE-FMR: A Sham-controlled Randomized Trial of 
Transcatheter Indirect Mitral Annuloplasty in Heart Failure Patients with 
Functional Mitral Regurgitation. Presented at TCT 2018, San Diego, CA.

SOURCE: Cardiac Dimensions

CONTACT: Laurie Masonson, laurie@greymattermarketing.com, +1 (917) 459-6164