Country for PR: United Kingdom
Contributor: PR Newswire Europe
Thursday, May 27 2021 - 17:00
AsiaNet
Menarini Silicon Biosystems launches new breakthrough DEPArray(TM) PLUS image-based cell sorter to isolate rare cells with single cell precision
BOLOGNA, Italy and HUNTINGDON VALLEY, Pa., May 27, 2021 /PRNewswire-AsiaNet/ --

DEPArray(TM) PLUS – the new automated and versatile platform to investigate 
pre-selected rare cell populations from various samples with 100% purity, now 
enhanced with 9 fluorescent channels and remarkably improved user experience 



Menarini Silicon Biosystems, a pioneer of liquid biopsy and single cell 
technologies, announced today the launch of the new highly automated 
DEPArray(TM) PLUS+, now available with 9 fluorescent channels. This robust 
image-based cell-sorting technology combines microelectronics and microfluidics 
in a unique platform to isolate rare cells from mixed cellular samples. Its 
optimized, intuitive interface allows researchers to obtain the desired target 
cells with a 100% purity and minimal operator interaction. The built-in 
software leads to a rapid selection of cells with a high level of accuracy, 
reproducibility, and quality images thanks to its fluorescent microscope 
resolution. The system is compatible with a variety of rare cell suspensions, 
including live and fixed cells, small cell loads, Formalin-Fixed 
Paraffin-Embedded (FFPE) tissues and liquid biopsies. Sorting of rare cells 
with DEPArray PLUS has become more effortless and precise than ever before.

DEPArray PLUS additional fluorescent channels provide expanded capabilities to 
better characterize different cell populations from complex heterogeneous 
samples. Once individual or pools of cells are isolated, researchers can 
conduct precise molecular investigations. "The DEPArray PLUS can complement the 
CELLSEARCH(R) platform, the Gold Standard for circulating tumor cells 
enrichment, to perform further molecular analyses and clinical research using 
the captured CTCs, since it features a unique automated workflow to isolate 
cells with very limited operator intervention and improved standardization of 
the process," commented Professor Leon WMM Terstappen, MD, PhD, Chair of the 
Department of Medical Cell BioPhysics at the University of Twente, The 
Netherlands. 

DEPArray PLUS is the latest evolution of the DEPArray technology with unique 
new features to optimize the user experience, reduce hands-on time and speed up 
sample processing. These include an automated notification system informing 
users directly on their mobile device upon the completion of each step of a run 
and a faster workflow thanks to a new cartridge with enhanced microfluidics and 
the implementation of pre-set parameters for identification and recovery of 
target cells. 

Researchers have the flexibility to prepare their samples according to their 
own protocol or use optimized sample preparation kits for various inputs 
including blood, FFPE tissue and forensic evidence. The system is able to 
identify and isolate extremely low numbers of target cells from a minimal input 
sample volume. DEPArray PLUS is fully integrated with blood samples prepared 
with the Menarini Silicon Biosystems CTC enrichment technologies, CELLSEARCH(R) 
and CELLMAG(TM), allowing further isolation and delivery of 100% pure single 
cells ready for genetic analysis.

For Fabio Piazzalunga, President and CEO of Menarini Silicon Biosystems "We are 
proud to provide the new powerful version of DEPArray technology for rare cell 
sorting with full automation capability: it is a revolutionary platform on 
which we will continue to add innovative features thereby opening new horizons 
for patient-centered precision therapies"

About DEPArray(TM) PLUS
DEPArray(TM) PLUS is an automated, image-based platform combining fluorescence 
and brightfield microscopy  to digitally sort target cells with 100% purity. 
This proprietary technology allows the gentle sorting of single rare cells from 
different samples such as enriched blood, FFPE tissues and forensic mixtures. 
The image gallery provides high resolution information to review, select and 
sort target cells for subsequent molecular characterization. The key new 
features of the system lie in the expanded 9 fluorescent channels, improved 
automation, faster single cell recovery and enhanced user experience.
For more information please refer to www.siliconbiosystems.com/deparray-plus. 

About Menarini Silicon Biosystems
Menarini Silicon Biosystems offers unique rare cell technologies and solutions 
that provide clinical researchers with access to unparalleled resolution in the 
study of cells and their molecular characterization.
Menarini Silicon Biosystems [ 
https://c212.net/c/link/?t=0&l=en&o=2974193-1&h=2883067015&u=http%3A%2F%2Fwww.siliconbiosystems.com%2F&a=Menarini+Silicon+Biosystems 
], based in Bologna, Italy, and Huntingdon Valley, Pa., U.S., is a wholly owned 
subsidiary of the Menarini Group, a multinational pharmaceutical, biotechnology 
and diagnostics company headquartered in Florence, Italy, with more than 17,000 
employees in 140 countries.

+For research use only. Not for use in diagnostic procedures.

Contact:  Linda Pavy -  linda.pavy@bcw-global.com 

Logo - https://mma.prnewswire.com/media/1362208/Menarini_Logo.jpg

Source: Menarini Silicon Biosystems