Innodem Neurosciences announced today that it has signed a multi-year 
partnership agreement with Novartis Pharmaceuticals Canada Inc. (Novartis) to 
conduct a breakthrough clinical trial to help people living with multiple 
sclerosis (MS).

Innodem's AI-powered, patented, eye tracking software technology is embodied in 
a mobile application that turns a tablet into a device capable of capturing and 
analyzing Eye Movement Biomarkers (EMBs) and Gaze Mapping Biomarkers (GMBs) to 
assist a clinician's diagnosis and monitor MS disease progression. 

Digital EMB and GMB tests are non-invasive and can be completed in minutes in 
the clinic's waiting room or by the patient at home. Remote self-testing is a 
major advantage during a pandemic and for people living with MS residing in 
rural areas who cannot easily access a neurologist. 

"The financing from Novartis will fund a carefully designed cross-sectional and 
longitudinal MS study that will last until 2027. As a practicing neurologist, 
I'm hopeful that the study will validate just how Innodem's technology can 
assist clinicians in monitoring disease progression as early as possible to 
improve MS treatment and patient outcomes," said Dr. Etienne de Villers-Sidani, 
cognitive neurologist, main founder and Chief Executive Officer of Innodem.

"This partnership is the result of an ongoing collaboration that was 
architected over the past two years. It embodies our common goal and commitment 
to improving quality of care for people living with MS globally," added Marc 
Reeves, co-founder and Chief Business Officer of Innodem.

"At Novartis, we are committed to innovation and becoming the leaders in the 
health tech space. After reviewing existing solutions, we selected Innodem's 
proprietary eye tracking technology and believe it to be the most promising and 
one that can easily scale due to its ease-of-use. We anticipate that the trial 
will confirm its relevancy so that more people living with MS and treating 
clinicians can have access to it in Canada and across the world," commented 
Andrea Marazzi, Country Pharma Organization Head, Novartis Pharmaceuticals 
Canada Inc.

Over the course of the trial, people living with MS will test twice a month and 
the data will be correlated with the current gold standard Expanded Disability 
Status Scale (EDSS), Brief International Cognitive Assessment for MS (BICAMS) 
and Multiple Sclerosis Functional Composite (MSFC) scores to assist clinicians 
in detecting subtle changes indicative of disease progression and that may not 
show up using magnetic resonance imaging (MRI).

Innodem management believes that the multi-year trial will demonstrate that 
novel digital EMBs and GMBs can measure these changes accurately, easily and 
cost-effectively. "A clinician whose patient shows objective signs of 
progressive MS may recommend a better adapted treatment which could, if 
detected early, prevent this individual from developing further disability. No 
practical companion diagnostic test currently exists to detect progressive MS, 
and I believe EMBs and GMBs can fill that important gap," added Dr. de 
Villers-Sidani.

About INNODEM NEUROSCIENCES 

Founded in 2016, Innodem Neurosciences has developed patented mobile digital 
biomarking technology of neurodegenerative diseases such as Multiple Sclerosis, 
Alzheimer's disease, Parkinson's disease and related disorders, Frontotemporal 
Dementia and related disorders and Cancer-Related Cognitive Impairment ("chemo 
brain"). This novel eye-tracking and cognition testing technology is embodied 
in a HIPAA/PIPEDA compliant system consisting of an intuitive tablet 
application connected to a cloud-based AI infrastructure. The app is made up of 
a series of tasks that are completed in minutes, where a user's eye movement is 
recorded in data sets called Eye Movement Biomarkers (EMBs) and Gaze Mapping 
Biomarkers (GMBs). Innodem's core team, led by cognitive neurologist & CEO Dr. 
Eìtienne de Villers-Sidani, is composed of an intersectional group of 
neuroscientists, software engineers, data scientists, healthcare professionals 
and serial entrepreneurs. The company's mission is to provide easier ways to do 
remote testing for all stages of neurodegenerative diseases and cancer-related 
cognitive impairment to improve quality of care and patient outcomes, at unseen 
levels of user-friendliness and cost-effectiveness for the global health 
system. For further information, please consult www.innodemneurosciences.com 

Contact: Valerie Gonzalo, AGO Communications, 514-923-1549, valerie@agocom.ca

SOURCE: Innodem Neurosciences