Country for PR: Australia
Contributor: Medianet International
Thursday, November 04 2021 - 01:00
AsiaNet
Gold Technology for Immune Response Cancer Therapy Licensed to OncoTEX
AUSTIN, Texas, Nov. 3, 2021 /Medianet International-AsiaNet/ --

OncoTEX Inc. (OncoTEX), a US oncology company and member of The iQ Group Global 
portfolio, is pleased to announce it has acquired a gold compound platform 
technology that induces the body’s immune system to destroy cancer cells.

The technology has been developed by the University of Texas at Austin, Georgia 
Southern University, and Wright State University; and licensed to OncoTEX. This 
technology will expand OncoTEX’s TEX Core platform, a world-first oncology drug 
platform designed to create innovative therapies capable of overcoming multiple 
limitations seen within current cancer therapeutics.

OncoTEX Chief Executive Officer, Dr. Jonathan F. Arambula, emphasized the 
critical importance of the novel technology due to its ability to induce the 
unique immune mechanism known as immunogenic cell death.

"Of more than 2000 known small molecule cancer therapeutics, very few have been 
validated to induce such a response," Dr. Arambula said.

"Of these, most only exhibit this as an auxiliary mechanism as opposed to the 
compound’s primary function. Our Gold compound platform will allow us to design 
compounds that specifically target these mechanisms. Research has shown that 
the compound is a much more potent sensitizer of immunogenic cell death than 
other agents such as platinum."

This new class of gold-based proprietary compounds represents a unique 
mechanism of immunotherapy action, in that the cancer cells are attacked in 
conjunction with the human body’s natural immune system. The gold-based 
compounds have the ability to enter cancer cells and fight them from the inside 
while disrupting the tumors, making them visible to the human immune system. 
This disruption starts a cascade to create killer T-cells that then attack and 
destroy the remaining cancer.

OncoTEX will commence a series of rigorous studies, in collaboration with the 
University of Texas at Austin, to evaluate these compounds over the coming 
months to determine the full-scale of their potential application in fighting 
cancers.

"The primary application of these compounds involves the targeting and 
treatment of solid tumors. We have identified their ability to do this 
effectively. Following further tests, we will evaluate their application for 
blood cancers and other diseases," Dr. Arambula said.

"This technology is very novel in terms of design, approach, and potential 
applications. We will continue discovery research to identify a potential 
clinical candidate. After our evaluation, we will move our identified clinical 
candidate into preclinical development."

CEO of The iQ Group Global and Executive Chairman of OncoTEX, Dr. George 
Syrmalis, said, “This new addition to our existing compound portfolio is 
extremely important not just for OncoTEX, but also for the modality of oncology.

"The compound introduces a novel mode of action, demonstrating tumor-specific 
immune responses and reinstating immunosurveillance. It is expected that 
through this gold-induced immunogenic cell death, we will be able to provide 
significant complements to immune checkpoint inhibitors. I speculate that this 
mode of action may emerge as a mainstream of cancer treatment in the near 
future."

About OncoTEX Inc.
OncoTEX Inc is an oncology company and a member of the bioscience investment 
enterprise The iQ Group Global. OncoTEX Inc owns TEX Core, a novel oncology 
drug platform that enables the development of well-tolerated, MRI-detectable 
cancer therapeutics that target drug-sensitive and drug-resistant solid tumors. 
Find out more ( https://oncotexinc.com/)

About The iQ Group Global
The iQ Group Global is a group of companies that find, fund and develop 
bioscience discoveries to create life-changing medical innovations. Recognized 
by The Australian Financial Review for the second consecutive year as one of 
the country’s Most Innovative Companies in 2020, The iQ Group Global’s flagship 
innovations include the Biosensor Platform and TEX Core, a first-in-class 
oncology drug platform with the ability to develop a pipeline of novel oncology 
compounds. Visit our website: https://theiqgroupglobal.com/

Media Contact:
James Gorman
+61-2-8239-5400
james.gorman@theiqgroupglobal.com

SOURCE: OncoTEX Inc.