Country for PR: China
Contributor: PR Newswire Asia (China)
Friday, April 29 2022 - 22:00
AsiaNet
Biocytogen Enters into Antibody Agreement with Merck
BEIJING, April 29, 2022 /PRNewswire-AsiaNet/ --

Biocytogen Pharmaceuticals (Beijing) Co., Ltd. (Biocytogen) announced that it 
has entered into an evaluation and option agreement with Merck to grant them a 
sole license to evaluate Biocytogen's proprietary antibodies against at least 
three distinct targets with an option to acquire some of the assets at a later 
date for therapeutic product development for all uses worldwide.

Under the agreement, Biocytogen will provide Merck antibodies directed against 
at least three targets specified by them from Biocytogen's Project Integrum 
(also called HiTS Platform), which are generated by leveraging Biocytogen's 
proprietary RenMiceTM Platform. Merck will carry out feasibility tests and be 
responsible for further development and commercialization of the products if 
exercising an option. Additional targets subject to mutual discretion may be 
included under this agreement.

Dr. Yuelei Shen, President and CEO of Biocytogen, said: "Thanks to Merck's 
recognition of our proprietary platform and antibody discovery capabilities, we 
believe that differentiated candidates generated from our innovative models and 
discovery platform can quickly advance novel antibody-based therapeutics. Our 
RenMiceTM-based Project Integrum aims to discover antibodies against more than 
1,000 targets. We welcome collaboration with partners worldwide to realize the 
full potential of this platform."

About Biocytogen

Biocytogen Pharmaceuticals (Beijing) Co., Ltd. is a global biotech company that 
drives the research and development of new drugs with innovative technologies. 
The company is committed to becoming a global headstream of new drugs to bring 
benefits to patients worldwide. Based on the fully human antibody RenMabTM and 
RenLiteTM mice for fully human antibody production with robust humoral 
responses, highly diverse antibody repertoires and superior affinity, 
Biocytogen has integrated its platforms in monoclonal and bispecific antibody 
development platforms, in vivo drug efficacy screening platforms and strong 
clinical development ability to streamline the entire drug development process. 
Biocytogen has launched Project Integrum, the world's first large-scale 
antibody discovery screening program adopting an evidence-based in vivo 
efficacy screening methodology to concurrently generate and screen antibodies 
against over 1,000 potential druggable targets, most of which have not been 
explored in clinical trials yet. With the implementation of Project Integrum, 
Biocytogen has entered ongoing collaborations with dozens of partners worldwide 
to produce many first-in-class and/or best-in-class antibody drugs. 
Biocytogen's pipeline includes 12 core products among which 2 products are in 
phase II multi-regional clinical trials (MRCTs) and 2 products are in phase I. 
Headquartered in Beijing, Biocytogen has branches in Haimen Jiangsu, Shanghai, 
Boston, USA and Heidelberg, Germany.

About Merck

Merck, a leading science and technology company, operates across healthcare, 
life science and electronics. Around 60,000 employees work to make a positive 
difference to millions of people's lives every day by creating more joyful and 
sustainable ways to live. From advancing gene editing technologies and 
discovering unique ways to treat the most challenging diseases to enabling the 
intelligence of devices – the company is everywhere. In 2021, Merck generated 
sales of € 19.7 billion in 66 countries.

Scientific exploration and responsible entrepreneurship have been key to 
Merck's technological and scientific advances. This is how Merck has thrived 
since its founding in 1668. The founding family remains the majority owner of 
the publicly listed company. Merck holds the global rights to the Merck name 
and brand. The only exceptions are the United States and Canada, where the 
business sectors of Merck operate as EMD Serono in healthcare, MilliporeSigma 
in life science, and EMD Electronics.

Source:Biocytogen

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