Country for PR: United Kingdom
Contributor: PR Newswire Europe
Tuesday, August 02 2022 - 09:00
AsiaNet
Novel and fast typing method developed to control monkeypox by Molecular Biology Systems (MBS) in collaboration with the Amsterdam UMC and Danish Rigshospitalet
GOES, Netherlands, Aug. 2, 2022 /PRNewswire-AsiaNet/ --

In the worldwide effort to control monkeypox, a novel and fast typing method to 
trace monkeypox virus strains was developed by Dutch company Molecular Biology 
Systems (MBS) in collaboration with the department of Medical Microbiology & 
Infectious Disease Prevention of the Amsterdam UMC and researchers of the 
Danish Rigshospitalet. Apart from being fast, this new method allows for 
analysis of multiple samples simultaneously. This way, genetic characterization 
of monkeypox virus can be used in source- and contact analyses and help 
determine the measures of choice. Analyzing multiple samples simultaneously, 
reduces cost per sample, meaning more insight for the same cost. A photo can be 
found https://www.nextgenpcr.com/product/mbs-nextgenpcr-ultrafast-thermocycler/:

The method has first been tested in the Amsterdam region; this led to new 
insights regarding the genetic diversity of monkeypox virus. This method was 
employed investigating the infection of the first child in the Netherlands. The 
characterization of mutations in the virus from the child was compared to other 
monkeypox viruses in the region. In a publication from July 21, 2022, in the 
widely read scientific journal Euro Surveillance the research into this case 
and the infectious chain are described. Using source- and contact analyses, no 
link with other cases was found. Possibly more undetected infections exist than 
assumed until now.

(Publication Euro Surveillance: 
https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2022.27.29.2200552 
)

An important bonus of this newly developed typing method is the usability for 
other viruses as well. By integrating this technique in source- and contact 
surveillance early stage, earlier insight into the spread of novel viruses can 
be acquired. This will enable fast, concrete, and accurate action.

The above is in line with the WHO strategy of surveillance of viruses 
worldwide, specifically monkeypox. Second meeting of the International Health 
Regulations (2005) (IHR) Emergency Committee regarding the multi-country 
outbreak of monkeypox (who.int)

Multiple leading international laboratories have indicated their intention to 
use this method for the genomic surveillance of monkeypox. 

About Molecular Biology Systems
Molecular Biology Systems, B.V., founded in 2015, is a molecular biology 
solutions company based in the Netherlands. Our NextGenPCR thermocycler uses 
patented technology to reduce PCR amplification from hours to minutes. 
NextGenPCR, the PCR technology of the future, available now.

Website: https://www.nextgenpcr.com/

Source: Molecular Biology Systems
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