Country for PR: China
Contributor: PR Newswire Asia (China)
Monday, February 20 2023 - 16:12
AsiaNet
Significant Progress Made on the Trivalent Recombinant Protein COVID-19 Vaccine against Subvariants including XBB.1.5 and BA.5 by WestVac Biopharma
CHENGDU, China, Feb. 20, 2023 /PRNewswire-AsiaNet/ --

Recently, with the support of the National Key R&D Program of China, following 
the clinical trial approval for Recombinant Variant COVID-19 Vaccine (Sf9 cell) 
approved by NMPA, WestVac Biopharma (Guangzhou) Co., Ltd. (hereinafter referred 
to as "WestVac Biopharma (Guangzhou)")  has made significant progress on the 
development of the trivalent recombinant protein COVID-19 vaccine against the 
latest prevalent subvariants including XBB.1.5 and BA.5, which is one of the 
first trivalent recombinant protein vaccines targeting XBB.1.5 worldwide.

Taking advantage of the rapid response of the internationally advanced insect 
cell expression platform in recombinant protein vaccine production, WestVac 
Biopharma (Guangzhou) has constructed the vector within one month, and produced 
the trivalent recombinant protein vaccine of high purity and quality for human 
use. It is an entirely synthetic vaccine. The subunit vaccine antigen is 
precisely designed based on the structure of the targeting S-RBD and HR protein 
of XBB.1.5 and BA.5 subvariants, and can self-assemble into stable trimeric 
protein particles. Study revealed that the vaccine induced high titers of 
neutralizing antibodies against Omicron XBB.1.5, BQ.1, BF.7, BA.5, BA.2.75 and 
other subvariants, suggesting that it is a broad-spectrum COVID-19 vaccine 
against multiple prevalent subvariants at home and abroad such as XBB.1.5, 
BQ.1, BF.7 and BA.5. At present, WestVac Biopharma is proactively engaged with 
the national authorities, and striving to meet the national approval 
requirements as soon as possible for the trivalent recombinant protein 
vaccine.The mission is to use WestVac BioPharma's power to aid in the fight 
against new variants of novel coronavirus!

WestVac Biopharma (Guangzhou) is a wholly-owned subsidiary of WestVac Biopharma 
Co., Ltd. located in the Innovative Vaccine Production Base in the Knowledge 
City of Guangzhou Economic Development Zone. With the production lines of a 
combined 5000L to be constructed soon for insect cell recombinant protein 
vaccine and nasal spray vaccine, it will have an annual production capacity of 
500 million doses of vaccines.

WestVac Biopharma Co., Ltd., the parent company, is an innovative 
biopharmaceutical company integrating vaccine R&D, production and sales. From 
2021 to 2022, WestVac Biopharma was selected successfully on the list of 
unicorn companies for two consecutive years. Coviccine® --Recombinant COVID-19 
Vaccine (Sf9 cell) developed by WestVac Biopharma has shown satisfactory safety 
and immunogenicity in clinical trial with 70.95% protective efficacy against 
Omicron subvariants, which is one of the most effective vaccines in preventing 
symptomatic COVID-19 cases with Omicron subvariants in the world. In December 
2022, Coviccine® has been approved by the national authority for emergency use 
and already been in the bidding process and supplied for vaccination in 
multiple provinces. In the meantime, Recombinant Variant COVID-19 vaccine (Sf9 
cell) developed by WestVac Biopharma has recently received the Approval for 
Clinical Trial by NMPA, the phase I/II clinical trials will soon begin.


SOURCE: WestVac BioPharma Co., Ltd.

Image Attachments Links:

   Link: https://iop.asianetnews.net/view-attachment?attach-id=438015

   Caption: WestVac BioPharma Co., Ltd.

Attachments
1.jpg
Translations

Japanese